Jeffrey D Lifson Selected Research

Proteins (Proteins, Gene)

1/2022	A cellular trafficking signal in the SIV envelope protein cytoplasmic domain is strongly selected for in pathogenic infection.
11/2019	Preferential Small Intestine Homing and Persistence of CD8 T Cells in Rhesus Macaques Achieved by Molecularly Engineered Expression of CCR9 and Reduced Ex Vivo Manipulation.
1/2018	Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques.
4/2015	Relative expression levels of the HLA class-I proteins in normal and HIV-infected cells.
12/2013	The frequency of α₄β₇(high) memory CD4⁺ T cells correlates with susceptibility to rectal simian immunodeficiency virus infection.
10/2013	Immune clearance of highly pathogenic SIV infection.
2/2013	DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge.
1/2013	Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives.
3/2012	Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques.
1/2009	Double-stranded RNA analog poly(I:C) inhibits human immunodeficiency virus amplification in dendritic cells via type I interferon-mediated activation of APOBEC3G.

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Jeffrey D Lifson Research Topics

Disease

132	Infections 04/2024 - 10/2002
50	Viremia 12/2023 - 02/2003
31	HIV Infections (HIV Infection) 12/2023 - 02/2003
26	Acquired Immunodeficiency Syndrome (AIDS) 01/2022 - 12/2003
11	Disease Progression 01/2018 - 01/2008
10	Virus Diseases (Viral Diseases) 12/2023 - 11/2008
6	Persistent Infection 12/2019 - 12/2013
4	Inflammation (Inflammations) 12/2023 - 03/2013
4	Coinfection 11/2014 - 04/2004
3	Neoplasms (Cancer) 01/2022 - 01/2018
3	Herpes Simplex 01/2018 - 02/2014
3	Fibrosis (Cirrhosis) 03/2015 - 02/2007
2	Communicable Diseases (Infectious Diseases) 11/2019 - 12/2018
2	Neurocognitive Disorders (Clerambault Syndrome) 01/2018 - 01/2016
2	Sexually Transmitted Diseases (Sexually Transmitted Disease) 01/2014 - 09/2012
1	Central Nervous System Infections (Central Nervous System Infection) 04/2024
1	Lymphopenia (Lymphocytopenia) 01/2022
1	Vaccinia 11/2020
1	Vesicular Stomatitis 11/2020
1	Body Weight (Weight, Body) 10/2020
1	Rubella (German Measles) 01/2020
1	Papillomavirus Infections 01/2018
1	Liver Diseases (Liver Disease) 01/2018
1	Lentivirus Infections 01/2017
1	Tuberculosis (Tuberculoses) 01/2017

Drug/Important Bio-Agent (IBA)

46	VaccinesIBA 01/2023 - 02/2003
19	Antiviral Agents (Antivirals)IBA 12/2023 - 09/2003
17	RNA (Ribonucleic Acid)IBA 04/2024 - 03/2002
17	DNA (Deoxyribonucleic Acid)IBA 11/2020 - 10/2002
15	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2002
12	Viral RNAIBA 12/2023 - 10/2002
10	MIV 150IBA 12/2017 - 09/2008
10	Anti-Infective Agents (Microbicides)IBA 02/2014 - 04/2009
9	AntibodiesIBA 01/2021 - 02/2003
8	Glycoproteins (Glycoprotein)IBA 11/2023 - 02/2004
8	Broadly Neutralizing AntibodiesIBA 01/2022 - 08/2015
8	EpitopesIBA 01/2022 - 10/2002
8	Monoclonal AntibodiesIBA 01/2020 - 03/2013
8	Viral DNAIBA 01/2020 - 10/2002
7	AIDS VaccinesIBA 01/2021 - 06/2005
7	CarrageenanIBA 01/2018 - 11/2012
7	Zinc Acetate FDA Link 12/2017 - 01/2011
6	Interleukin-15 (Interleukin 15)IBA 12/2019 - 06/2006
6	AntigensIBA 11/2019 - 07/2004
5	Neutralizing AntibodiesIBA 01/2021 - 02/2003
5	CytokinesIBA 01/2019 - 04/2009
5	SAIDS VaccinesIBA 01/2017 - 07/2005
4	Bone Marrow Stromal Antigen 2IBA 01/2020 - 12/2013
4	Reverse Transcriptase InhibitorsIBA 02/2014 - 11/2009
3	Immunoglobulin G (IgG)IBA 12/2019 - 02/2013
3	env Gene ProductsIBA 01/2018 - 10/2014
3	ChemokinesIBA 11/2016 - 04/2009
3	Complement System Proteins (Complement)IBA 11/2014 - 01/2011
3	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 11/2014 - 11/2012
2	N,N'- (2,2'- (hexa- 2,4- diyne- 1,6- diylbis(oxy))bis(2,3- dihydro- 1H- indene- 2,1- diyl))bis(1- (2- cyclohexyl- 2- (2- (methylamino)propanamido)acetyl)pyrrolidine- 2- carboxamide)IBA 01/2021 - 10/2020
2	IgG Receptors (Fc gamma RI)IBA 01/2020 - 04/2010
2	Immunoglobulins (Immunoglobulin)IBA 12/2018 - 05/2016
2	CD40 Ligand (CD40L)IBA 11/2016 - 02/2004
2	Histone Deacetylase InhibitorsIBA 12/2015 - 11/2014
2	HLA-B Antigens (HLA-B)IBA 11/2015 - 11/2007
2	Interferon Type IIBA 07/2014 - 04/2008
2	Interferon-alpha (Interferon Alfa)IBA 12/2013 - 04/2008
2	IntegrinsIBA 09/2013 - 06/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2013 - 03/2005
2	Interleukin-10 (Interleukin 10)IBA 03/2013 - 08/2008
2	HIV Reverse TranscriptaseIBA 09/2012 - 09/2008
2	NucleosidesIBA 09/2012 - 11/2009
2	CollagenIBA 03/2011 - 02/2007
2	Viral ProteinsIBA 10/2010 - 08/2005
2	OligodeoxyribonucleotidesIBA 04/2004 - 05/2003
1	Small Cytoplasmic RNAIBA 04/2024
1	Cell Surface ReceptorsIBA 11/2023
1	PerforinIBA 01/2022
1	Fingolimod Hydrochloride (FTY720)FDA Link 01/2022
1	Amino Acids FDA Link 01/2022
1	MicroRNAs (MicroRNA)IBA 01/2022
1	pembrolizumabIBA 01/2022
1	HIV AntigensIBA 01/2021
1	Viral AntigensIBA 11/2020
1	ProteomeIBA 11/2020
1	DNA VaccinesIBA 01/2020
1	Rubella VaccineIBA 01/2020
1	Ribosomal DNA (rDNA)IBA 01/2019
1	vesatolimodIBA 01/2019
1	Griffithsia griffithsin proteinIBA 01/2018
1	Minocycline (Cyclops)FDA LinkGeneric 01/2018
1	Contraceptive Agents (Contraceptives)IBA 12/2017
1	Levonorgestrel (Plan B)FDA LinkGeneric 12/2017
1	HLA-DR Antigens (HLA-DR)IBA 07/2017
1	BCG Vaccine FDA Link 01/2017
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 11/2016

Therapy/Procedure

22	Therapeutics 05/2023 - 11/2003
17	Art Therapy 12/2023 - 11/2007
10	Highly Active Antiretroviral Therapy (HAART) 12/2019 - 11/2009
4	Immunotherapy 01/2020 - 02/2009
3	Aftercare (After-Treatment) 01/2022 - 01/2016
2	Drug Therapy (Chemotherapy) 01/2022 - 01/2017
1	Intravenous Administration 01/2022
1	Treatment Delay 12/2019
1	Duration of Therapy 12/2019